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基因缺失疫苗是一种新型疫苗设计方法，通过删除病原体的特定基因来产生更安全和有效的疫苗。Gene-deleted vaccine has emerged as a promising approach to vaccine development, as it allows for the creation of attenuated vaccines with reduced virulence. This type of vaccine has shown great potential in preventing infectious diseases, including viral and bacterial infections. By removing specific genes from the pathogen, the vaccine can stimulate a protective immune response without causing disease. The development and application of gene-deleted vaccines have paved the way for innovative strategies in disease prevention and control. Numerous studies have demonstrated the efficacy and safety of gene-deleted vaccines, making them a promising tool in the fight against infectious diseases. As research in this area progresses, gene-deleted vaccines hold significant promise for addressing current and emerging public health challenges.
基因缺失疫苗,Gene-deleted vaccine
1)Gene-deleted vaccine基因缺失疫苗
1.The study was conducted to determine the effect of vaccination with PR gene-deleted vaccine SA215(gE~(-)/gI~(-)/TK~(-)) on the establishment of latency and succedent reactivation of virulent PRV.通过建立能鉴别野毒和疫苗毒的多重PCR,确定试制的伪狂犬病基因缺失疫苗SA215对强毒潜伏感染的建立及随后被激活的影响。
英文短句/例句
1.Study on Pseudorabies Virus Gene-deleted Vaccine, SA215 Strain;伪狂犬病基因缺失疫苗SA215研究
2.Construction and immunization of an attenuated vaccine candidate enteropathogenic Escherichia coli O45肠致病性大肠杆菌O45基因缺失疫苗菌株的构建及其免疫原性分析
3.Construction of bp26 Gene Deletion Mutant in B.Melitensis Vaccine Strain M5-90 and Evaluation of Safety and Immunogenicity马耳他布鲁氏菌M5-90 bp26基因缺失疫苗株的构建及安全性和免疫原性评估
4.Construction, Identification and Experimental Immunization of Goatpox Virus Gene Deleted Mutant and DNA Vaccine;山羊痘病毒基因缺失毒株及DNA疫苗的构建、鉴定和实验免疫
5.Study on the Pathogenicity of Actinobacillus Pleuropneumoniae ApxIV and Gene Deleted Attenuated Vaccine胸膜肺炎放线杆菌毒素ApxIV的致病性及基因缺失弱毒疫苗的研究
6.Research of Vaccine about Human Immunodeficiency Virus Genes Recombinant with Poliovirus;人免疫缺陷性病毒基因重组脊髓灰质炎病毒疫苗的实验研究
7.genetic immunization基因免疫接种[采用基因疫苗进行接种]
8.Study on Molecular Marker and Virulence Deleted Vaccine Strain △YZ-2 of B.abortus;布鲁氏菌分子标记、毒力缺失疫苗株△YZ-2的研究
9.Study on the Immune Responses Induced by Toxoplasma Gondii DNA Vaccine with Gene Encoding P30 and P30-ROP2;弓形虫P30单基因疫苗与P30-ROP2复合基因疫苗免疫小鼠的实验研究
10.Immunotherapy Targeting for Hepato-Cellular Carcinoma with DNA Vaccine of Legumain Gene in Mice;Legumain基因DNA疫苗抗肝癌免疫研究
11.Development of DNA Vaccines with Multi-gene of Foot-and-Mouth Disease Virus Serotype O;O型口蹄疫病毒多基因DNA疫苗的研制
12.STUDIES ON RECOMBINANT VACCINE OF NEWCASTLE DISEASE VIRUS IN CHICKENS;鸡新城疫基因工程亚单位疫苗的研究
13.Effect of Myostatin gene vaccine on immunized miceMyostatin基因疫苗动物免疫效果的初步研究
14.Discussion on laboratory causes for immunization failure with hepatitis B vaccine乙型肝炎疫苗免疫失败实验室原因的探讨
15.Factors associated with failure in immunization with hepatitis B vaccine乙肝疫苗免疫失败的影响因素及补救对策
16.Cause Analysis and Preventive Measures of Immunity Failure of Rabies Vaccination接种狂犬病疫苗免疫失败原因分析及预防对策
17.Immunogenicity of Genetic Recombinant Vaccines Against Foot-and-Mouth Disease Virus (FMDV);口蹄疫病毒基因重组疫苗的实验免疫研究
18.Study on DNA Vaccine and Recombinant Live Vaccine Expressing Linear Epitopes of FMDV;FMDV线性表位基因疫苗和重组活疫苗的构建及基因疫苗免疫原性研究
相关短句/例句
TK deleted vaccineTK基因缺失疫苗
3)gene-deleted mutants基因缺失疫苗株
4)PRV gene-deleted vaccinePRV基因缺失疫苗
5)three gene-deleted vaccine(SA215)三基因缺失疫苗SA215株
6)gene-deleted vaccine against pseudorabies伪狂犬病基因缺失疫苗
1.In order to provide the effective vaccine for the immunoprophylaxis of swine pseudorabies,agene-deleted vaccine against pseudorabies was prepared using a previously constructed mutant,PrV HB-98(TK~-/gG~-/LacZ~+ mutant),that were grown with primary embryo fibroblast cells.为了提供有效的伪狂犬病疫苗,用鸡胚成纤维细胞扩大培养了PrV HB-98突变株(TK-/gG-/LacZ+),研制了伪狂犬病基因缺失疫苗,并对该疫苗经肌肉接种、经口等免疫途径的最小免疫剂量进行了测定,同时也对4批疫苗的安全性、效力、免疫期和保存期进行了检测;同时将4批疫苗用于免疫23个猪场的母猪、新生仔猪和育肥猪进行区域试验。
延伸阅读
基因工程疫苗基因工程疫苗
基因工程疫苗（engineering vaccine）使用dna重组生物技术，把天然的或人工合成的遗传物质定向插入细菌、酵母菌或哺乳动物细胞中，使之充分表达，经纯化后而制得的疫苗。应用基因工程技术能制出不含感染性物质的亚单位疫苗、稳定的减毒疫苗及能预防多种疾病的多价疫苗。如把编码乙型肝炎表面抗原的基因插入酵母菌基因组，制成dna重组乙型肝炎疫苗；把乙肝表面抗原、流感病毒血凝素、单纯疱疹病毒基因插入牛痘苗基因组中制成的多价疫苗等。基因工程疫苗是将病毒的保护性抗原编码的基因片段克隆入表达载体,用以转染细胞或真核细胞微生物及原核细胞微生物后得到的产物.
Key Insights into Gene-deleted Vaccine Development 英语短句和例句： - Gene-deleted vaccines have shown promising results in preclinical trials indicating their potential as a new approach to vaccination. - The use of gene-deleted vaccines offers a novel strategy to induce robust immune responses against infectious diseases. - Researchers are exploring the use of gene-deleted vaccines to target specific pathogens and improve vaccine efficacy. - The development of gene-deleted vaccines represents a significant advancement in the field of immunization with broad implications for public health.
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